Abstract | OBJECTIVE: DATA SOURCES: REVIEW METHODS: Narrative review. All articles relating to post-implant meningitis without any restriction in study designs were assessed and information extracted. RESULTS: The presence of inner ear trauma as a result of surgical technique or cochlear implant electrode array design was associated with a higher risk of post-implant meningitis. Laboratory data demonstrated the effectiveness of pneumococcal vaccination in preventing meningitis induced via the hematogenous route of infection. Fibrous sealing around the electrode array at the cochleostomy site, and the use of antibiotic-coated electrode array reduced the risk of meningitis induced via an otogenic route. CONCLUSION: The recent scientific data support the U.S. Food and Drug Administration recommendation of pneumococcal vaccination for the prevention of meningitis in implant recipients. Nontraumatic cochlear implant design, surgical technique, and an adequate fibrous seal around the cochleostomy site further reduce the risk of meningitis.
|
Authors | Benjamin P C Wei, Robert K Shepherd, Roy M Robins-Browne, Graeme M Clark, Stephen J O'Leary |
Journal | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
(Otolaryngol Head Neck Surg)
Vol. 143
Issue 5 Suppl 3
Pg. S9-14
(Nov 2010)
ISSN: 1097-6817 [Electronic] England |
PMID | 20970694
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
|
Copyright | Copyright © 2010 American Academy of Otolaryngology–Head and Neck Surgery Foundation. Published by Mosby, Inc. All rights reserved. |
Chemical References |
- Anti-Bacterial Agents
- Pneumococcal Vaccines
|
Topics |
- Anti-Bacterial Agents
(administration & dosage)
- Cochlear Implantation
(adverse effects)
- Cochlear Implants
(adverse effects)
- Drug Delivery Systems
- Ear, Inner
(injuries, pathology)
- Electrodes
- Humans
- Meningitis, Pneumococcal
(etiology, microbiology, prevention & control)
- Pneumococcal Vaccines
(administration & dosage)
- Prosthesis-Related Infections
(etiology, microbiology, prevention & control)
- Risk Factors
- Streptococcus pneumoniae
|