Basilar skull fracture: outcome of acute care without antibiotic prophylaxis in a Nigerian neurosurgical unit.

A prospective observational study of the in-hospital outcome of the management of BSF without antibiotic prophylaxis in a Nigerian neurosurgical unit.
All cases of HI with clinical diagnosis of BSF over an 8-month period were reviewed. Their demographic, clinical, and in-hospital outcome parameters were analysed. We also compared some clinical and outcome characteristics between this study group and a contemporary cohort of patients in our unit with Head Injury but without CSF leak
There were 47 cases. The CSF leak was from the nostrils in 18 (38.3%), the ears in 16 (34.04%), and both ears and nostrils in 12 (25.53%). The cause of injury was road accidents in 91%, and the severity of the Head Injury was mild, moderate and severe respectively in 42.55, 25.53 and 31.91%. Meningitis occurred in 2 patients (4.25%); in-hospital outcome was good in 68.1% and poor in 31.9% and this was significantly (p < 0.05) affected primarily by the severity of the brain injuries. These in-hospital outcome rates and their determinants were similar to those in our unit's contemporary cohort of Head Injury without BSF.
Management of traumatic BSF without antibiotic prophylaxis in a developing country setting has not been accompanied with an increased rate of unfavourable outcome.
AuthorsAmos Olufemi Adeleye, Oladapo Olayemı
JournalTurkish neurosurgery (Turk Neurosurg) Vol. 20 Issue 4 Pg. 430-6 (Oct 2010) ISSN: 1019-5149 [Print] Turkey
PMID20963690 (Publication Type: Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Acute Disease
  • Adult
  • Anti-Bacterial Agents
  • Cerebrospinal Fluid Otorrhea (mortality, surgery)
  • Developing Countries (statistics & numerical data)
  • Glasgow Coma Scale
  • Hospital Mortality
  • Humans
  • Meningitis (mortality)
  • Nigeria (epidemiology)
  • Postoperative Complications (mortality)
  • Retrospective Studies
  • Skull Fracture, Basilar (mortality, surgery)
  • Treatment Outcome

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