Pre-erythrocytic stage malaria parasites: non-circumsporozoite protein antigens.

Abstract

A series of non-circumsporozoite proteins found in pre-erythrocytic parasites are being developed as putative vaccine candidates. It is anticipated that these will be useful in addition to, rather than instead of, the CS (circumsporozoite) vaccines. It is likely that a greater understanding of the basic biology of malaria parasite-host relationships will lead to development of improved malarial vaccines.

• Authors: M R Hollingdale, M Aikawa, G X Chen, J F Meis, K Sakhuja, B Sina, J D Zhu
• Journal: Bulletin of the World Health Organization (Bull World Health Organ) Vol. 68 Suppl Pg. 178-80 ( 1990) ISSN: 0042-9686 [Print] Switzerland
• PMID: 2094584 (Publication Type: Journal Article)

Chemical References

• Antigens, Protozoan
• Antigens, Surface
• Heat-Shock Proteins
• Vaccines, Synthetic

Topics

• Animals
• Antigens, Protozoan (isolation & purification)
• Antigens, Surface (isolation & purification)
• Heat-Shock Proteins (isolation & purification)
• Humans
• Plasmodium berghei (immunology)
• Plasmodium falciparum (immunology)
• Vaccines, Synthetic (isolation & purification)