A case of AL amyloidosis with renal rupture.

Abstract

We report a 59-year-old woman with AL amyloidosis who presented with massive bleeding from the right kidney, in whom emergency surgery proved to be life saving. The patient had been diagnosed as having AL amyloidosis 16 years previously. After 5 years, hemodialysis had been initiated. In 2007, a large right-sided perinephric, intracapsular hematoma was detected. Right nephrectomy was performed and the patient recovered with no sequelae. Histopathological examination revealed a greater degree of amyloid deposition in the resected kidney than that at the time of diagnosis. Amyloid angiopathy may promote bleeding.

• Authors: Yuko Iwabuchi, Mitsuyo Itabashi, Tetsuri Yamashita, Kunio Kawanishi, Chiari Kojima, Takashi Takei, Junko Arai, Kazuho Honda, Kosaku Nitta
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 49 Issue 19 Pg. 2129-32 ( 2010) ISSN: 1349-7235 [Electronic] Japan
• PMID: 20930441 (Publication Type: Case Reports, Journal Article)

Chemical References

• Amyloid
• amyloid protein AL

Topics

• Adult
• Amyloid (metabolism)
• Amyloidosis (complications, metabolism, therapy)
• Female
• Hematoma (diagnostic imaging, etiology, surgery)
• Hemorrhage (etiology, surgery)
• Humans
• Kidney Diseases (etiology, metabolism, surgery, therapy)
• Nephrectomy
• Renal Dialysis
• Rupture, Spontaneous (etiology)
• Tomography, X-Ray Computed