Glucose information for tight glycemic control: different methods with different challenges.

Abstract

Rigorous glucose control is essential for prevention of diabetes-related complications in diabetes patients. Even without diabetes, tight glucose control is beneficial in hospitalized, critically ill patients. Actually, three different glucose measurement methods are used: (1) hand held devices, (2) blood-gas analyzers, and (3) laboratory analyzers in core laboratories. Each method is subject to specific challenges and limitations that can affect the overall system performance. In this article, we aim to demonstrate that even glucose measurement results from core laboratories (professional laboratory systems) do not necessarily reflect the absolute "true" glucose level of a patient.

• Authors: Christian Weber, Kurt Neeser
• Journal: Journal of diabetes science and technology (J Diabetes Sci Technol) Vol. 4 Issue 5 Pg. 1269-75 (Sep 01 2010) ISSN: 1932-2968 [Electronic] United States
• PMID: 20920450 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2010 Diabetes Technology Society.

Chemical References

• Blood Glucose
• Glucose 1-Dehydrogenase
• Glucose Oxidase
• Hexokinase

Topics

• Blood Gas Monitoring, Transcutaneous (methods, standards)
• Blood Glucose (metabolism)
• Blood Glucose Self-Monitoring (methods, standards)
• Critical Illness
• Diabetes Mellitus (blood)
• Glucose 1-Dehydrogenase
• Glucose Oxidase
• Hexokinase
• Humans
• Laboratories (standards)
• Reproducibility of Results