[Peripancreatic sporadic gastrinoma].

Abstract

BACKGROUND:

The peri-pancreatic sporadic gastrinoma represents a paradigm of digestive endocrinology. It was originally an abnormal secretion of gastrin fits the syndrome Zollinger-Ellison.

AIM:

The objective of our work is to clarify the diagnostic strategy and therapeutic conduct of gastrinoma.

CASE:

We report the case of a patient aged 42 years, hospitalized for bleeding duodenal ulcer, revealed a Zollinger-Ellison syndrome. The different explorations have shown that it was a primitive péripancréatique sporadic gastrinoma. In surgery, we discover a rétropancréatique tumor associated to a stenosis post-bulbar ulcer. It was conducted a enucleation of the tumor with vagotomie troncular and gastroenteroanastomosis. The forecast was favourable with normalization of the values of gastrinémie.

CONCLUSION:

The sporadic gastrinoma is rare, its emphasis is increasingly being facilitated by the technology of modern medical imaging, belonging to a polyendocrinopathie must be systematic search. Treatment of pancreatic gastrinoma is multidisciplinary. Surgery is the only cure for this disease.

• Authors: Wael Rebai, Rachid Ksantini, Faouzi Chebbi, Amin Makni, Sofiene Ayadi, Amin Daghfous, Fadhel Fterich, Haykal Bedioui, Adel Ammous, Mohamed Jouini, Montasser Kacem, Zoubeir Ben Safta
• Journal: La Tunisie medicale (Tunis Med) Vol. 88 Issue 10 Pg. 761-4 (Oct 2010) ISSN: 0041-4131 [Print] Tunisia
• Vernacular Title: Gastrinome sporadique péri-pancréatique.
• PMID: 20890828 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Adult
• Gastrinoma (pathology, surgery)
• Humans
• Male
• Pancreatic Neoplasms (pathology, surgery)