Abstract |
We evaluated longitudinal rates of Kaposi's sarcoma and trends in CD4 cell counts at the time of Kaposi's sarcoma diagnosis during the HIV epidemic (1985-2008). Although rates of Kaposi's sarcoma have decreased, cases are now occurring at higher CD4 cell counts over time, with more than one-third of cases diagnosed in 2002-2008 occurring at CD4 cell counts of at least 350 cells/μl. These data support future studies evaluating the impact of highly active antiretroviral therapy initiation at higher CD4 cell counts to further reduce Kaposi's sarcoma.
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Authors | Nancy F Crum-Cianflone, Katherine Huppler Hullsiek, Anuradha Ganesan, Amy Weintrob, Jason F Okulicz, Brian K Agan, Infectious Disease Clinical Research Program HIV Working Group |
Journal | AIDS (London, England)
(AIDS)
Vol. 24
Issue 18
Pg. 2881-3
(Nov 27 2010)
ISSN: 1473-5571 [Electronic] England |
PMID | 20827160
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S.)
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Topics |
- AIDS-Related Opportunistic Infections
(epidemiology, immunology)
- Adult
- Antiretroviral Therapy, Highly Active
- CD4 Lymphocyte Count
- Epidemics
- Female
- HIV-1
- Humans
- Male
- Sarcoma, Kaposi
(epidemiology, immunology)
- Viral Load
- Young Adult
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