Abstract | BACKGROUND: Hyperthermic intraperitoneal chemoperfusion ( HIPEC) is an innovative treatment of the peritoneal carcinomatosis with potential iatrogenicity. This observational study was designed to improve our understanding of HIPEC's impact on the renal and respiratory functions, on temperature, blood cells counts, body fluids/ electrolytes and acid-base balance. METHODS: RESULTS: The main changes were appearing just after the HIPEC procedure: increased diuresis, lactic acidosis, hyponatremia and hyperglycaemia (despite aggressive intravenous insulin therapy). In our series, there was no renal failure or impact on blood cells counts until the 7(th) day, neither some changes on the arterial blood gases. CONCLUSION:
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Authors | J Raft, M Parisot, F Marchal, S Tala, E Desandes, J-M Lalot, F Guillemin, D Longrois, C Meistelman |
Journal | Annales francaises d'anesthesie et de reanimation
(Ann Fr Anesth Reanim)
Vol. 29
Issue 10
Pg. 676-81
(Oct 2010)
ISSN: 1769-6623 [Electronic] France |
Vernacular Title | Retentissements hydroélectrolytiques et acidobasiques de la chimiohyperthermie intrapéritonéale. |
PMID | 20797835
(Publication Type: English Abstract, Journal Article)
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Copyright | Copyright © 2010 Elsevier Masson SAS. All rights reserved. |
Chemical References |
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Topics |
- Adult
- Antineoplastic Agents
(administration & dosage)
- Body Fluids
- Carcinoma
(drug therapy)
- Combined Modality Therapy
- Female
- Humans
- Hyperthermia, Induced
(adverse effects)
- Male
- Middle Aged
- Peritoneal Neoplasms
(drug therapy)
- Peritoneum
- Retrospective Studies
- Water-Electrolyte Imbalance
(etiology)
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