Local warming at injection site helps alleviate pain after rocuronium administration.

Abstract

PURPOSE:

Various strategies have been proposed to reduce discomfort of pain after rocuronium injection. These studies have shown pretreatment of drugs such as fentanyl and lidocaine to be effective. In a prospective randomized study, we evaluated whether pretreatment with local warming at injection site using an air-warming device could effectively alleviate pain induced by rocuronium.

METHODS:

Ninety patients undergoing spinal surgeries were randomly divided into two groups: group C (control) and group T (treatment). Patients in group T were subjected to warming at 40°C for 1 min prior to injecting 1 ml (10 mg) of rocuronium at the site of venous access. Patients were then assessed for any discomfort and to quantify their discomfort on a 5-point scale.

RESULTS:

Age, sex, and weight were comparable between the two groups. Pain on rocuronium administration was reported by 88.9% patient in group C versus 66.7% in group T (p < 0.05). Severe pain was significantly less in group T (35.6% vs. 8.9%).

CONCLUSION:

Application of warmth over the vascular access prior to rocuronium administration effectively reduces injection-related pain.

• Authors: Charu Mahajan, Girija Prasad Rath, Parmod Kumar Bithal, Hemanshu Prabhakar, Rahul Yadav, Surya Kumar Dube
• Journal: Journal of anesthesia (J Anesth) Vol. 24 Issue 6 Pg. 845-8 (Dec 2010) ISSN: 1438-8359 [Electronic] Japan
• PMID: 20737278 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Androstanols
• Neuromuscular Nondepolarizing Agents
• Rocuronium

Topics

• Adolescent
• Adult
• Androstanols (adverse effects)
• Catheters, Indwelling
• Female
• Hot Temperature (therapeutic use)
• Humans
• Injections (adverse effects)
• Male
• Middle Aged
• Neuromuscular Nondepolarizing Agents (adverse effects)
• Pain (chemically induced, prevention & control)
• Pain Measurement (drug effects)
• Prospective Studies
• Rocuronium
• Young Adult