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[Evaluation of the efficacy of continuous epidural block with low concentration of local anesthetics in patients with ureterolithiasis].

Abstract
Forty patients with ureterolithiasis were studied to evaluate the efficacy of a continuous epidural block with local anesthetics. The patients were randomly allocated into 3 groups: first group (n = 7) received continuous epidural administration of 1% mepivacaine at a rate of 2 ml.hr-1; second group (n = 19) received intermittent bolus administration of the same anesthetic 4-5 times daily; and third group (control group, n = 14) was treated by conventional therapy including infusion of Ringer's solution and diuretics. Among 3 groups, a comparison of the rate of abortion of ureter stone, the rate of mobilization of stone, and the frequency of operation was performed. The rate of abortion in group 1 was significantly higher than those of group 2 and control. The rate of mobilization of stone in group 1 tended to be higher than group 2 and control. Also the frequency of operation in group 1 tended to be lower than group 2. Effect of continuous administration with 1% mepivacaine in patient with ureterolithiasis was comparable to that of intermittent bolus administration of 2% mepivacaine or 0.5% bupivacaine reported. We conclude that the continuous block with 1% mepivacaine is effective and safe for treating the patient with ureterolithiasis.
AuthorsS Shigeomi, H Mitsuhata, S Matsumoto, M Yabe, K Ohtaka
JournalMasui. The Japanese journal of anesthesiology (Masui) Vol. 40 Issue 5 Pg. 728-31 (May 1991) ISSN: 0021-4892 [Print] Japan
PMID2072515 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
Chemical References
  • Mepivacaine
Topics
  • Adult
  • Aged
  • Anesthesia, Epidural
  • Female
  • Humans
  • Lithotripsy
  • Male
  • Mepivacaine
  • Middle Aged
  • Time Factors
  • Ureteral Calculi (therapy)

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