Two cases of corneal ulcer due to methicillin-resistant Staphylococcus aureus in high risk groups.
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| Abstract |
Considering the popular use of antibiotic-containing eyedrops in Korea, it is important to know the emerging antibiotic-resistant strains of bacteria before treating infectious eye diseases. This is especially important in high-risk groups because of the high incidence of resistant infections and the subsequent treatment requirements. We report two cases of methicillin-resistant Staphylococcus aureus (MRSA) corneal ulcers in high-risk groups. The first case involved a patient who had keratitis after using antibiotic- and steroid-containing eyedrops to treat a corneal opacity that developed after repeated penetrating keratoplasty. The second case involved a patient who used antibiotic-containing eyedrops and a topical lubricant on a regular basis for >1 month to treat exposure keratitis due to lagophthalmos. The second patient's problems, which included a persistent superficial infiltration, developed after brain tumor surgery. Both cases showed MRSA on corneal culture, and the corneal ulcers improved in both patients after the application of vancomycin-containing eyedrops. In conclusion, MRSA infection should be considered in corneal ulcers that have a round shape, mild superficial infiltration, and slow progression, especially in high-risk groups. This report includes descriptions of the characteristic features, antibiotic sensitivities, prevention, and successful treatment with vancomycin-containing eyedrops for MRSA corneal ulcers.
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| Authors | Kyung-Min Lee, Hyun-Soo Lee, Man-Soo Kim |
| Journal | Korean journal of ophthalmology : KJO (Korean J Ophthalmol) Vol. 24 Issue 4 Pg. 240-4 (Aug 2010) ISSN: 2092-9382 [Electronic] Korea (South) |
| PMID | 20714389 (Publication Type: Case Reports, Journal Article) |
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