HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[A case of inflammatory breast cancer successfully treated with intra-arterial infusion of high-dose epirubicin].

Abstract
A 56-year-old female with extensive inflammatory breast cancer was treated with intra-arterial infusion chemotherapy using a high dose of epirubicin. One cycle consisted of epirubicin; 150 mg (day 1, 4, 7) and daily administration of tamoxifen; 40 mg. After completion of 2 cycles of the regimen, both the main tumor and the extensive inflammatory skin lesion completely disappeared (CR). Hair loss, gastrointestinal disorders and leukopenia (nadir; 1,600) were the side effects encountered, but all of them were reversible. These findings suggested that dose-escalation of epirubicin was effective, and that cases with extensive skin involvement were also candidates for this modality.
AuthorsY Takatsuka, J Gofuku, T Katoh, Y Okamura, K Kobayakawa, T Kawahara
JournalGan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 18 Issue 8 Pg. 1363-6 (Jul 1991) ISSN: 0385-0684 [Print] Japan
PMID2069407 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Tamoxifen
  • Epirubicin
Topics
  • Administration, Oral
  • Breast Neoplasms (drug therapy, pathology)
  • Drug Administration Schedule
  • Epirubicin (administration & dosage)
  • Female
  • Humans
  • Inflammation
  • Infusions, Intra-Arterial
  • Middle Aged
  • Tamoxifen (administration & dosage)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: