Superiority of an essential oil mouthrinse when compared with a 0.05% cetylpyridinium chloride containing mouthrinse: a six-month study.

Abstract

OBJECTIVE:

To evaluate the antiplaque/antigingivitis effectiveness of an essential oils containing mouthrinse as compared to a 0.05% cetylpyridinium chloride mouthrinse.

METHOD:

Generally healthy subjects with mild to moderate levels of plaque and gingivitis participated in a 6-month, examiner-blind, single centre, randomised, parallel-group controlled clinical trial. They were randomised into three mouthrinse groups--control (C), 0.05% cetylpyridinium chloride (CPC), or a fixed combination of essential oils (EO). Subjects received a dental prophylaxis at baseline and rinsed twice daily in addition to their usual oral hygiene for six months. Plaque Index and Modified Gingival Index were determined at 3 and 6 months.

RESULTS:

At 6 months, the EO group exhibited statistically significantly lower mean scores for MGI and PI than CPC (32.4% and 56.2% reductions, respectively). Compared to control, EO provided statistically significantly lower mean MGI and PI scores (36.3% and 69.7 %, respectively). The CPC group showed statistically significantly lower mean MGI and PI scores than the C group (5.8% and 30.7%, respectively).

CONCLUSION:

This study demonstrated the superiority of an EO rinse compared to a 0.05% CPC rinse in reducing plaque and gingivitis and confirmed that the daily use of an EO containing mouthrinse can provide a clinically significant benefit in reducing plaque and gingivitis.

• Authors: Naresh C Sharma, Marcelo W B Araujo, Mei Miau Wu, James Qaqish, Christine H Charles
• Journal: International dental journal (Int Dent J) Vol. 60 Issue 3 Pg. 175-80 (Jun 2010) ISSN: 0020-6539 [Print] England
• PMID: 20684443 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Infective Agents, Local
• Drug Combinations
• Mouthwashes
• Oils, Volatile
• Salicylates
• Terpenes
• Listerine
• Cetylpyridinium

Topics

• Adult
• Anti-Infective Agents, Local (administration & dosage, therapeutic use)
• Cetylpyridinium (administration & dosage, therapeutic use)
• Dental Plaque (prevention & control)
• Dental Plaque Index
• Dental Prophylaxis
• Drug Combinations
• Female
• Follow-Up Studies
• Gingivitis (prevention & control)
• Humans
• Male
• Mouthwashes (therapeutic use)
• Oils, Volatile (therapeutic use)
• Oral Hygiene
• Periodontal Index
• Salicylates (therapeutic use)
• Single-Blind Method
• Terpenes (therapeutic use)
• Treatment Outcome