Abstract | PURPOSE: MATERIALS AND METHODS: RESULTS: A total of 59 patients met study inclusion criteria. Necrosis, teratoma and cancer were identified in 31%, 46% and 24% of retroperitoneal specimens, and in 73%, 17% and 10% of liver specimens, respectively. Concordance between retroperitoneal and liver histology was 49% overall, including 94% for necrosis, 26% for teratoma and 36% for cancer. Liver necrosis alone was found in 94%, 70% and 50% of patients with retroperitoneal necrosis, teratoma and cancer, respectively. CONCLUSIONS: The overall rate of histological discordance between retroperitoneal and liver histology was 51% with 73% of all liver specimens containing necrosis only. Retroperitoneal necrosis is highly predictive of hepatic necrosis (94%). Management for liver lesions at post- chemotherapy retroperitoneal lymph node dissection must be individualized. Observation may be warranted for liver lesions requiring complicated hepatic surgery regardless of retroperitoneal pathology.
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Authors | Niels-Erik B Jacobsen, Stephen D W Beck, Lewis E Jacobson, Richard Bihrle, Lawrence H Einhorn, Richard S Foster |
Journal | The Journal of urology
(J Urol)
Vol. 184
Issue 3
Pg. 949-53
(Sep 2010)
ISSN: 1527-3792 [Electronic] United States |
PMID | 20643453
(Publication Type: Journal Article)
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Copyright | 2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. |
Topics |
- Adolescent
- Adult
- Child
- Hepatectomy
- Humans
- Liver
(pathology)
- Liver Neoplasms
(secondary, surgery)
- Lymph Node Excision
(methods)
- Male
- Necrosis
- Neoplasms, Germ Cell and Embryonal
(drug therapy, secondary, surgery)
- Predictive Value of Tests
- Retroperitoneal Space
- Retrospective Studies
- Testicular Neoplasms
(drug therapy, surgery)
- Time Factors
- Young Adult
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