Focal epithelial hyperplasia (Heck disease) related to highly active antiretroviral therapy in an HIV-seropositive child. A report of a case, and a review of the literature.

Abstract

Focal epithelial hyperplasia is increasingly frequently observed in rural South African communities. HIV-seropositive subjects have a higher prevalence of oral human papillomavirus (HPV) infections than immunocompetent subjects; and paradoxically, the introduction of highly active antiretroviral therapy for treatment of HIV-seropositive subjects is associated with increased frequency of focal epithelial hyperplasia. We describe a case of focal epithelial hyperplasia in an HIV-seropositive child receiving highly active antiretroviral therapy, who was successfully treated by using diode laser ablation.

• Authors: L Feller, R A G Khammissa, N H Wood, V Malema, R Meyerov, J Lemmer
• Journal: SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging (SADJ) Vol. 65 Issue 4 Pg. 172-5 (May 2010) ISSN: 1029-4864 [Print] South Africa
• PMID: 20632701 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Antiretroviral Therapy, Highly Active (adverse effects)
• Child
• Facial Dermatoses (virology)
• Female
• Focal Epithelial Hyperplasia (chemically induced, surgery)
• HIV Seropositivity (drug therapy)
• Humans
• Laser Therapy
• Papillomavirus Infections (diagnosis)
• Warts (virology)