Abstract | BACKGROUND: AIMS: To evaluate the relationship between a favourable outcome in patients with acute ischaemic stroke and specific demographic, clinical and laboratory variables and cardiovascular drug pretreatment. METHODS: RESULTS: Patients with no in-hospital mortality, a HAMT score of >6 and no ADL impairment were more likely to be younger at baseline and have a lower blood glucose level and a systolic blood pressure (SBP) between 120 and 180 mmHg, a higher plasma total cholesterol level, a lower white blood cell count, and a lower Charlson Index (CI) score, a higher rate of pretreatment with ACE-inhibitors, calcium channel blockers and a lower rate of pretreatment with heparin. CONCLUSIONS: Predictors of good outcome, in terms of in-hospital mortality and cognitive and functional performance at discharge, included higher SBP at admission between 120 and 180 mmHg, a SBP plasma total cholesterol levels, a lower CI score, and pretreatment with ACE-inhibitors, calcium channel blockers and anti-platelets.
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Authors | Antonino Tuttolomondo, Riccardo Di Sciacca, Domenico Di Raimondo, Claudio Pedone, Sergio La Placa, Antonio Pinto, Giuseppe Licata |
Journal | International journal of cardiology
(Int J Cardiol)
Vol. 151
Issue 3
Pg. 318-22
(Sep 15 2011)
ISSN: 1874-1754 [Electronic] Netherlands |
PMID | 20598761
(Publication Type: Comparative Study, Journal Article, Multicenter Study)
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Copyright | Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. |
Chemical References |
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Topics |
- Aged
- Aged, 80 and over
- Brain Ischemia
(drug therapy, mortality)
- Cardiovascular Agents
(administration & dosage)
- Databases, Factual
(trends)
- Female
- Follow-Up Studies
- Hospital Mortality
(trends)
- Humans
- Italy
(epidemiology)
- Male
- Pharmacoepidemiology
(trends)
- Retrospective Studies
- Stroke
(drug therapy, mortality)
- Treatment Outcome
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