Massive hepatic necrosis with gastric, splenic, and pancreatic infarctions after ethanol ablation for hepatocellular carcinoma.

Abstract

Hepatic necrosis after ethanol ablation for hepatocellular carcinoma (HCC), although rare, is well known and described, particularly in patients with chronic liver disease. The present report describes a rare case of massive hepatic necrosis with partial gastric, splenic, and pancreatic infarctions after local treatment of liver HCC with ethanol ablation and discusses the reasons for this complication. With the increasing use of percutaneous techniques to treat liver tumors, it is imperative for the interventional radiologist to be aware of the potential vascular complications of these techniques. An appreciation of vascular anatomy via multidetector computed tomography (CT) and/or magnetic resonance (MR) angiography is important when planning image-guided interventions.

• Authors: David Da Ines, Emmanuel Buc, Virginie Petitcolin, Renaud Flamein, Valérie Lannareix, Anca Achim, Jean-Marc Garcier
• Journal: Journal of vascular and interventional radiology : JVIR (J Vasc Interv Radiol) Vol. 21 Issue 8 Pg. 1301-5 (Aug 2010) ISSN: 1535-7732 [Electronic] United States
• PMID: 20598566 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright (c) 2010 SIR. Published by Elsevier Inc. All rights reserved.

Chemical References

• Antineoplastic Agents
• Ethanol

Topics

• Aged
• Antineoplastic Agents (administration & dosage, adverse effects)
• Carcinoma, Hepatocellular (blood supply, diagnostic imaging, therapy)
• Chemical and Drug Induced Liver Injury (diagnostic imaging, etiology, therapy)
• Ethanol (administration & dosage, adverse effects)
• Humans
• Infarction (chemically induced, diagnostic imaging, therapy)
• Injections, Intralesional
• Liver Neoplasms (blood supply, diagnostic imaging, therapy)
• Male
• Necrosis
• Pancreas (blood supply)
• Severity of Illness Index
• Spleen (blood supply)
• Stomach (blood supply)
• Tomography, X-Ray Computed
• Treatment Outcome