Abstract | AIM: METHODS: Serum adiponectin and resistin levels were prospectively measured by enzyme immunoassay in 70 mothers and their 70 neonates. The study group included 30 neonates with macrosomia and the control group included 40 neonates that were appropriate for gestational age. The correlations of cord serum adiponectin and resistin with maternal serum adiponectin and resistin, birth weight, body mass index (BMI), and placental weight were analyzed. RESULTS: Serum adiponectin and resistin levels were significantly decreased in macrosomic mothers compared with those in control women. The levels of adiponectin and resistin were diminished in macrosomic babies in comparison with control newborns. Umbilical serum adiponectin levels were inversely correlated with birth weight, newborn BMI, and placental weight, but not with maternal serum adiponectin levels. Umbilical serum resistin levels had a positive correlation with maternal serum resistin and a negative correlation with birth weight, newborn BMI, and placental weight. In addition, maternal serum resistin levels were inversely correlated with newborn birth weight. CONCLUSION:
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Authors | Jing Wang, Shu-He Wang, Li-Xin Shang, Xing Dong, Xin Wang, Fang Zhang, Nan Wu, Li-Ming Xu, Yuan-Yuan Ye |
Journal | The journal of obstetrics and gynaecology research
(J Obstet Gynaecol Res)
Vol. 36
Issue 3
Pg. 533-7
(Jun 2010)
ISSN: 1447-0756 [Electronic] Australia |
PMID | 20598033
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Retracted Publication)
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Chemical References |
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Topics |
- Adiponectin
(blood)
- Body Mass Index
- Female
- Fetal Blood
(metabolism)
- Fetal Macrosomia
(blood)
- Humans
- Immunoenzyme Techniques
- Pregnancy
- Resistin
(blood)
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