Vitiligo after diphencyprone for alopecia areata.

Abstract

The topical immunotherapy is used to treat alopecia areata and recalcitrant warts since the 1970s. Diphencyprone is a contact sensitizer used to treat dermatological conditions resulting from as altered immunological state, such as extensive alopecia areata, being partially effective and safe. Side effects include local eczema with blistering, regional lymphadenopathy and contact urticaria. Rare adverse effects include an erythema multiforme-like reaction, hyperpigmenttion, hypopigmentation, and vitiligo. We report a 30-year-old, Brazilian male who developed vitiligo lesions following DPCP therapy for alopecia areata.

• Authors: Mario Cezar Pires, João Mauricio Martins, F Montealegre, Flávia Romero Gatti
• Journal: Dermatology research and practice (Dermatol Res Pract) Vol. 2010 Pg. 171265 ( 2010) ISSN: 1687-6113 [Electronic] Egypt
• PMID: 20585597 (Publication Type: Case Reports)