A rare case of segmental neurofibromatosis involving the sciatic nerve.

Abstract

Segmental neurofibromatosis (NF-5) is an extremely rare variant of neurofibromatosis involving a single extremity without pathologic features beyond the midline. A case of segmental neurofibromatosis involving the sciatic nerve and its branches is presented with a detailed description of the patient's preoperative findings plus postoperative course through 1-year follow-up. Clinical, histologic, and genetic findings are given along with a brief review of the literature on segmental neurofibromatosis. Last, treatment options and postoperative care recommendations are provided.

• Authors: Aron Trocchia, Alma Reyes, Jon Wilson, Kimberly Les
• Journal: American journal of orthopedics (Belle Mead, N.J.) (Am J Orthop (Belle Mead NJ)) Vol. 39 Issue 5 Pg. E42-5 (May 2010) ISSN: 1934-3418 [Electronic] United States
• PMID: 20567746 (Publication Type: Case Reports, Journal Article)

Chemical References

• S100 Proteins

Topics

• Adult
• Disease-Free Survival
• Female
• Humans
• Neurofibromatoses (pathology, physiopathology, surgery)
• Peripheral Nervous System Neoplasms (pathology, physiopathology, surgery)
• S100 Proteins (metabolism)
• Schwann Cells (metabolism)
• Sciatic Nerve (pathology, surgery)