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Urinary type IV collagen excretion predicts subsequent declining renal function in type 2 diabetic patients with proteinuria.

Abstract
Baseline urinary type IV collagen excretion was negatively correlated with the subsequent GFR change (r(s)=-0.39, p=0.04) in our cohort of 30 type 2 diabetic patients with proteinuria. Therefore, it could be used to predict subsequent declining renal function in type 2 diabetic patients with proteinuria.
AuthorsPisut Katavetin, Paravee Katavetin, Paweena Susantitaphong, Natavudh Townamchai, Khajohn Tiranathanagul, Kriang Tungsanga, Somchai Eiam-Ong
JournalDiabetes research and clinical practice (Diabetes Res Clin Pract) Vol. 89 Issue 2 Pg. e33-5 (Aug 2010) ISSN: 1872-8227 [Electronic] Ireland
PMID20542586 (Publication Type: Journal Article)
CopyrightCopyright 2010 Elsevier Ireland Ltd. All rights reserved.
Chemical References
  • Angiotensin-Converting Enzyme Inhibitors
  • Collagen Type IV
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Angiotensin-Converting Enzyme Inhibitors (therapeutic use)
  • Collagen Type IV (urine)
  • Diabetes Mellitus, Type 2 (drug therapy, physiopathology, urine)
  • Diabetic Nephropathies (pathology, urine)
  • Female
  • Glomerular Filtration Rate
  • Humans
  • Kidney Function Tests
  • Male
  • Middle Aged
  • Proteinuria (drug therapy, pathology, urine)

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