Extensive comedonal and cystic acne in Patau syndrome.

Abstract

Patau syndrome is a chromosomal disorder associated with multiple malformations caused by inheritance of an extra chromosome (trisomy 13). Some skin defects have been reported in patients with Patau syndrome, such as scalp defects, glabellar stains, deep palmar creases, rocker-bottom feet, convex soles, hyperconvextity of the nails, and multiple hemangiomas. To our knowledge, widespread comedonal and cystic acne have not been previously reported in Patau syndrome.

• Authors: Antonio Torrelo, Pablo Fernandez-Crehuet, Elena Del Prado, Pilar Martes, Angela Hernández-Martín, Verónica De Diego, Francisco Carapeto
• Journal: Pediatric dermatology (Pediatr Dermatol) Vol. 27 Issue 2 Pg. 199-200 ( 2010) ISSN: 1525-1470 [Electronic] United States
• PMID: 20537076 (Publication Type: Case Reports, Journal Article)

Chemical References

• Retinoids
• Clindamycin
• Erythromycin
• Benzoyl Peroxide

Topics

• Abnormalities, Multiple (diagnosis, genetics)
• Abscess (diagnosis, drug therapy, genetics)
• Acne Vulgaris (diagnosis, drug therapy, genetics)
• Benzoyl Peroxide (therapeutic use)
• Chromosomes, Human, Pair 13 (genetics)
• Clindamycin (therapeutic use)
• Erythromycin (therapeutic use)
• Face
• Female
• Humans
• Infant
• Retinoids (therapeutic use)
• Sebaceous Glands (abnormalities)
• Syndrome
• Trisomy (diagnosis, genetics)