[Intravascular large B-cell lymphoma with massive pulmonary lesions].

Abstract

A 61-year-old man was admitted to our hospital with dyspnea on effort. Neither computed tomography scan nor chest X-ray film detected any specific findings that could explain hypoxemia. Since (67)Ga scintigraphy showed abnormal uptake in the bilateral lungs, transbronchial lung biopsy (TBLB) was performed. The TBLB specimen was diagnosed as intravascular large B-cell lymphoma (IVLBCL). There was no involvement of any other organ considered typical of IVLBCL. In cases showing clinical findings such as hypoxia despite mild pulmonary radiographic changes, a definitive diagnosis should be made using methods such as TBLB with consideration given to the possibility of IVLBCL.

• Authors: Asumi Higashiyama, Satoshi Hashino, Masahiro Onozawa, Mutsumi Takahata, Kohei Okada, Kaoru Kahata, Natsuko Taniguchi, Yasuyuki Nasuhara, Kanako Kubota, Nozomu Fujimoto, Yoshihiro Matsuno, Masahiro Nishimura, Masahiro Asaka
• Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology (Rinsho Ketsueki) Vol. 51 Issue 5 Pg. 353-6 (May 2010) ISSN: 0485-1439 [Print] Japan
• PMID: 20534958 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Antibodies, Monoclonal
• Antibodies, Monoclonal, Murine-Derived
• Rituximab
• Vincristine
• Doxorubicin
• Cyclophosphamide
• Prednisolone

Topics

• Antibodies, Monoclonal (administration & dosage)
• Antibodies, Monoclonal, Murine-Derived
• Antineoplastic Combined Chemotherapy Protocols (administration & dosage, therapeutic use)
• Biopsy (methods)
• Cyclophosphamide (administration & dosage)
• Doxorubicin (administration & dosage)
• Humans
• Lung Neoplasms (diagnosis, drug therapy, pathology)
• Lymphoma, Large B-Cell, Diffuse (diagnosis, drug therapy, pathology)
• Male
• Middle Aged
• Positron-Emission Tomography
• Prednisolone (administration & dosage)
• Rituximab
• Vascular Neoplasms (diagnosis, drug therapy, pathology)
• Vincristine (administration & dosage)