HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Another "suspect": homeopathic agent associated with acute interstitial nephritis].

AbstractHISTORY AND CLINICAL FINDINGS:
A 70-year-old woman was admitted to hospital with fatigue, pallor and shortness of breath on mild exertion. In her past medical history only borderline hypertension and allergy to penicillin were to note.
INVESTIGATIONS:
Actual laboratory findings revealed renal failure with metabolic acidosis and hyperkalaemia. A normochrome normocytic anemia and secondary hyperparathyreoidism were suggestive of a subacute course. The renal biopsy showed histological features of a subacute tubulo-interstitial nephritis.
DIAGNOSIS, TREATMENT AND COURSE:
The chronic renal failure caused by an interstitial nephritis was treated with corticosteroids and hemodialysis treatment was started. The trigger for AIN could not be found, there was no infectious or systemically disease nor a nephrotoxic medication identified. For nearly six months the patient had taken a homeopathic agent which is a dilution of penicillium chrysogenum. In case of a determined allergy to penicillin, an extract of the fungus producing penicillin could possibly cause an interstitial nephritis. The patient was dialysis-independent with a GFR about 8 - 10 ml/min at the time of discharge.
CONCLUSION:
With interstitial nephritis all agents should be considered a potential suspect, even homeopathic agents.
AuthorsG Türkoglu-Raach, H-J Gröne, T Sitter, M Fischereder
JournalDeutsche medizinische Wochenschrift (1946) (Dtsch Med Wochenschr) Vol. 135 Issue 24 Pg. 1224-7 (Jun 2010) ISSN: 1439-4413 [Electronic] Germany
Vernacular TitleEin weiterer "Verdächtiger": Homöopathikum mit akuter interstitieller Nephritis assoziiert.
PMID20533155 (Publication Type: Case Reports, Journal Article)
CopyrightGeorg Thieme Verlag KG Stuttgart New York.
Chemical References
  • Penicillins
  • Plant Extracts
Topics
  • Aged
  • Drug Hypersensitivity (complications, diagnosis)
  • Female
  • Glomerular Filtration Rate (drug effects)
  • Homeopathy
  • Humans
  • Kidney Failure, Chronic (chemically induced, diagnosis)
  • Nephritis, Interstitial (chemically induced, diagnosis)
  • Penicillins
  • Penicillium chrysogenum
  • Phytotherapy (adverse effects)
  • Plant Extracts (toxicity)
  • Risk Factors

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: