Abstract | BACKGROUND: METHODS: The benefits of lymphadenectomy were examined in 214 patients with a histological diagnosis of endometrial adenocarcinoma. Tumour characteristics were analysed with respect to the surgical and pathological stage. RESULTS: Of the 214 patients with endometrial adenocarcinoma, 171 (79.9%) were classified as FIGO stage I, 15 (7.0%) FIGO stage II, 21 (9.8%) FIGO stage III and 7 (3.3%) FIGO stage IV. One hundred and thirty four (62.6%) of the patients had a histological grade 1 tumour, while 56 (26.2%) and 24 (11.2%) had a histological grade 2 or grade 3 tumour, respectively. Lymphadenectomy was performed in 151 (70.6%) patients. Only 11 (5.1%) patients showed metastatic disease in the lymph nodes. The performance of a lymphadenectomy resulted in significantly increased cause-specific and overall survival, while progression-free survival was not affected by this operative procedure. CONCLUSIONS:
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Authors | Nina Bassarak, Thomas Blankenstein, Ansgar Brüning, Darius Dian, Florian Bergauer, Klaus Friese, Ioannis Mylonas |
Journal | BMC cancer
(BMC Cancer)
Vol. 10
Pg. 224
(May 21 2010)
ISSN: 1471-2407 [Electronic] England |
PMID | 20492712
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Aged
- Carcinoma, Endometrioid
(mortality, secondary, surgery)
- Chi-Square Distribution
- Disease-Free Survival
- Endometrial Neoplasms
(mortality, pathology, surgery)
- Female
- Humans
- Kaplan-Meier Estimate
- Lymph Node Excision
(mortality)
- Lymph Nodes
(pathology, surgery)
- Lymphatic Metastasis
- Middle Aged
- Neoplasm Staging
- Proportional Hazards Models
- Registries
- Retrospective Studies
- Time Factors
- Treatment Outcome
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