Abstract | INTRODUCTION: A triple antibiotic mixture of ciprofloxacin, metronidazole, and minocycline was used as an intracanal medicament in an attempt to disinfect the root canal system for revascularization of a tooth with a necrotic pulp. However, discoloration developed after applying the triple antibiotic mixture. METHODS: Six weeks after a triple antibiotic paste had been applied to the root canal of tooth #8 of a 7-year-old girl, the tooth showed a dark discoloration. An in vitro experiment with human extracted teeth was performed to determine which of the 3 antibiotics caused the tooth discoloration. Another experiment was then carried out to examine whether a currently used dentin bonding agent would prevent or reduce such discoloration. The degree of discoloration was assessed by using a colorimeter. RESULTS: CONCLUSIONS: The possible esthetic problems with the tooth color should be considered when using minocycline as a canal medication.
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Authors | Jong-Hyun Kim, Yuran Kim, Su-Jung Shin, Jeong-Won Park, Il-Young Jung |
Journal | Journal of endodontics
(J Endod)
Vol. 36
Issue 6
Pg. 1086-91
(Jun 2010)
ISSN: 1878-3554 [Electronic] United States |
PMID | 20478471
(Publication Type: Case Reports, Comparative Study, Journal Article, Randomized Controlled Trial)
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Copyright | Copyright 2010 American Association of Endodontists. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Acrylic Resins
- AdheSE cement
- Anti-Bacterial Agents
- Anti-Infective Agents
- Dental Disinfectants
- Dentin-Bonding Agents
- Drug Combinations
- Root Canal Irrigants
- Metronidazole
- Ciprofloxacin
- Minocycline
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Topics |
- Acrylic Resins
(chemistry)
- Anti-Bacterial Agents
(adverse effects)
- Anti-Infective Agents
(therapeutic use)
- Child
- Ciprofloxacin
(therapeutic use)
- Colorimetry
- Dental Disinfectants
(adverse effects)
- Dental Pulp Necrosis
(drug therapy, therapy)
- Dentin-Bonding Agents
(chemistry)
- Drug Combinations
- Female
- Follow-Up Studies
- Humans
- Incisor
(drug effects)
- Metronidazole
(therapeutic use)
- Minocycline
(adverse effects)
- Periapical Periodontitis
(drug therapy, therapy)
- Root Canal Irrigants
(adverse effects)
- Tooth Bleaching
(methods)
- Tooth Crown
(drug effects)
- Tooth Discoloration
(chemically induced, prevention & control)
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