[Albright's hereditary osteodystrophy: report of three cases].

Abstract

Albright's hereditary osteodystrophy includes an heterogeneous group of genetic diseases, including the pseudohypoparathyroidism type Ia and pseudo-pseudohypoparathyroidism. Features of this disease are: round faces, over-weight, subcutaneous calcifications and brachydactylia. Pseudohypoparathyroidism type Ia is associated with laboratory abnormalities such as hypocalcemia, and hyperphosphatemia due to parathormone resistance. Furthermore, these patients may present peripheral resistance to other hormones, such as gonadotrophins and thyroids. Pseudo-pseudohypoparathyroidism has no peripheral resistance to these hormones. We present three patients evaluated in our hospital with clinical manifestations of Albright's syndrome.

• Authors: María M Bujan, Andrea B Cervini, Virginia Fano, Adrián M Pierini
• Journal: Archivos argentinos de pediatria (Arch Argent Pediatr) Vol. 108 Issue 2 Pg. e24-7 (Apr 2010) ISSN: 1668-3501 [Electronic] Argentina
• Vernacular Title: Osteodistrofia hereditaria de Albright: presentación de tres casos clínicos.
• PMID: 20467695 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Adolescent
• Child
• Female
• Fibrous Dysplasia, Polyostotic (diagnosis)
• Humans
• Infant
• Male