Abstract | BACKGROUND: METHODS AND RESULTS: Between October 2004 and December 2008, 190 patients with non-rheumatic AF (122 males, age 71+/-10 years) who underwent transesophageal echocardiography (TEE) were enrolled and analyzed. All patients were examined for presence or absence of LA thrombus by TEE. CRP was measured within 1 week before the TEE examination. LA thrombus was detected in 19 patients (10%). Hypertension, hypertensive heart disease (HHD), valvular heart disease, ticlopidine, and CRP were univariate correlates of LA thrombus. By multivariate analysis, HHD (p<0.01), ticlopidine (p=0.01), and CRP (p=0.03) were independently associated with LA thrombus. A cut-off CRP value for identifying LA thrombus was 0.21mg/dl (sensitivity: 84%, specificity: 60%, positive predictive value: 19%, and negative predictive value: 97%). CONCLUSION: A high CRP is related to LA thrombus in patients with non-rheumatic AF.
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Authors | Tomoko Maehama, Hiroyuki Okura, Koichiro Imai, Ken Saito, Ryotaro Yamada, Terumasa Koyama, Akihiro Hayashida, Yoji Neishi, Takahiro Kawamoto, Kiyoshi Yoshida |
Journal | Journal of cardiology
(J Cardiol)
Vol. 56
Issue 1
Pg. 118-24
(Jul 2010)
ISSN: 0914-5087 [Print] Netherlands |
PMID | 20466519
(Publication Type: Journal Article)
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Copyright | Copyright 2010 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved. |
Chemical References |
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Atrial Fibrillation
(blood, diagnostic imaging, pathology)
- C-Reactive Protein
(analysis)
- Echocardiography
- Echocardiography, Transesophageal
- Female
- Heart Atria
(pathology)
- Humans
- Inflammation
(blood, complications)
- Male
- Middle Aged
- Thrombosis
(pathology)
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