Abstract | BACKGROUND: METHODS: A cohort of 570 patients with CRI who underwent intervention with DES (346 with SES and 224 with PES) were followed clinically up to 1 year and the clinical events were recorded and compared between groups. RESULTS: Baseline and procedural characteristics were similar, with a slightly higher number of diseased vessels in the SES group as compared to the PES group (2.3 +/- 0.9 vs 2.1 +/- 0.9, P = 0.06). The overall rates of major adverse cardiac events ( MACE) and stent thrombosis were similar. The PES group had lower revascularization rates when compared to the SES group. After covariate adjustment, however, there was no difference seen in target vessel revascularization between stent types (hazard ratio [HR]: 2.3 [0.8-6.2], P = 0.110). The strongest predictor of death and MACE at 1 year was the number of diseased vessels. CONCLUSIONS: Patients with CRI who undergo PCI with either SES or PES have similar repeat revascularization rates and acceptable stent thrombosis rates, although they continue to have high MACE and death rates.
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Authors | Asmir I Syed, Itsik Ben-Dor, Sara D Collins, Manuel A Gonzalez, Michael A Gaglia Jr, Rebecca Torguson, Lowell F Satler, William O Suddath, Augusto D Pichard, Joseph Lindsay, Ron Waksman |
Journal | Journal of interventional cardiology
(J Interv Cardiol)
Vol. 23
Issue 1
Pg. 33-9
(Feb 2010)
ISSN: 1540-8183 [Electronic] United States |
PMID | 20465718
(Publication Type: Journal Article)
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Chemical References |
- Antineoplastic Agents, Phytogenic
- Immunosuppressive Agents
- Paclitaxel
- Sirolimus
|
Topics |
- Aged
- Angioplasty, Balloon, Coronary
- Antineoplastic Agents, Phytogenic
(therapeutic use)
- Coronary Restenosis
(prevention & control)
- Coronary Thrombosis
(prevention & control)
- Drug-Eluting Stents
- Female
- Glomerular Filtration Rate
- Hospital Mortality
- Humans
- Immunosuppressive Agents
(therapeutic use)
- Incidence
- Male
- Multivariate Analysis
- Myocardial Infarction
(prevention & control)
- Paclitaxel
(therapeutic use)
- Proportional Hazards Models
- Renal Insufficiency, Chronic
(physiopathology)
- Retrospective Studies
- Risk Factors
- Sirolimus
(therapeutic use)
- Treatment Outcome
- United States
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