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[Treatment of adult patients with metastatic sarcoma: current shift in concepts].

Abstract
We describe herein the current concepts tested in clinical trials dedicated to patients with metastatic soft tissue sarcomas: identify predictive factors under anthracyclin-based regimens, identify patients beneficing from polychemotherapy, benefit of maintenance treatment, use of non-progression rate rather than response rate for selecting new drugs, histology-tailored or biological target-tailored second-line treatment.
AuthorsN Penel, F Watelle, M Vanhuyse, A Adenis
JournalBulletin du cancer (Bull Cancer) Vol. 97 Issue 6 Pg. 687-91 (Jun 2010) ISSN: 1769-6917 [Electronic] France
Vernacular TitleTraitement des sarcomes des tissus mous de l'adulte métastatiques: évolution actuelle des concepts.
PMID20462829 (Publication Type: English Abstract, Journal Article)
Chemical References
  • ridaforolimus
  • Doxorubicin
  • Sirolimus
Topics
  • Adult
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Doxorubicin (administration & dosage)
  • Humans
  • Sarcoma (drug therapy, pathology, secondary)
  • Sirolimus (administration & dosage, analogs & derivatives)
  • Soft Tissue Neoplasms (drug therapy, pathology)

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