[Linear accelerator-based stereotactic radiotherapy in combined treatment of skull base chordomas].

Abstract

Short-term results of postoperative stereotactic linear accelerator-based radiation treatment of 18 patients with cranial base chordomas are analyzed. Total dose was 70 Gy or more. Control of tumor growth confirmed by CT and/or MRI was achieved in 15 cases (83%). Only 1 patient had complication--visual deficit which resolved after 3 months. Control group consisted of 73 patients treated only surgically. 38% of cases in this group were recurrence-free. The study has demonstrated effectiveness of radiotherapy of skull base chordomas.

• Authors: D V Sidorkin, A V Golanov, U B Makhmudov, A N Shkarubo, S V Zolotova, G E Gorlachev, N V Arutiunov
• Journal: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko (Zh Vopr Neirokhir Im N N Burdenko) 2010 Jan-Mar Issue 1 Pg. 29-34 ISSN: 0042-8817 [Print] Russia (Federation)
• PMID: 20432560 (Publication Type: English Abstract, Journal Article)

Topics

• Adult
• Chondroma (mortality, pathology, radiotherapy)
• Disease-Free Survival
• Female
• Humans
• Male
• Retrospective Studies
• Skull Base Neoplasms (mortality, pathology, radiotherapy)