[The gonadotropin, prolactin and sex steroid content of the blood from the inferior cavernous sinuses and the adrenal and ovarian veins of women with Itsenko-Cushing disease].

Abstract

Results are reported of a study of the content of gonadotropins, prolactin and sex steroids in different regions of the vascular bed in women with Itsenko-Cushing disease. It was found that the content of gonadotropins were similar at all levels of the vascular bed indicating their secretion reduction in the pituitary. At the same time there was an increase of prolactin, testosterone, progesterone and cortisol in the blood of the ovarian, adrenal, peripheral and lower cavernous sinus veins. It is suggested that increased secretion of testosterone, progesterone and cortisol inhibits the production of gonadotropins and prolactin-inhibiting factor in the pituitary and leads to an increased prolactin level.

• Authors: R A Manusharova, I V Komissarenko, O G Iugrinov
• Journal: Vrachebnoe delo (Vrach Delo) Issue 3 Pg. 71-4 (Mar 1991) ISSN: 0049-6804 [Print] Ukraine
• Vernacular Title: Soderzhanie gonadotropinov, prolaktina i polovykh steroidov v krovi iz nizhnikh kavernoznykh sinusov, nadpochechnikovykh i iaichnikovykh ven u zhenshchin s bolezn'iu Itsenko--Kushinga.
• PMID: 2042357 (Publication Type: English Abstract, Journal Article)

Chemical References

• Gonadal Steroid Hormones
• Gonadotropins, Pituitary
• Prolactin

Topics

• Adrenal Glands (blood supply)
• Adult
• Cavernous Sinus
• Cushing Syndrome (blood, complications)
• Female
• Gonadal Steroid Hormones (blood)
• Gonadotropins, Pituitary (blood)
• Humans
• Ovary (blood supply)
• Polycystic Ovary Syndrome (blood, etiology)
• Prolactin (blood)
• Veins