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LASIK correction of vision in adults with unilateral amblyopia.

AbstractPURPOSE:
to evaluate the effects of laser refractive surgery in adult patients with mild to moderate amblyopia due to anisometropic myopia.
METHODS:
a retrospective review of 30 patients (60 eyes) with unilateral amblyopia (corrected distance visual acuity [CDVA] 0.6 or worse) who underwent simultaneous bilateral laser vision correction using the Technolas 217z excimer laser (Bausch & Lomb) was performed. Mean patient age was 31.03 ± 10.05 years (range: 18 to 53 years). Visual outcomes in the amblyopic eye were compared with those in the fellow nonamblyopic control eye of the same patient.
RESULTS:
mean preoperative CDVA improved in amblyopic eyes from 0.50 ± 0.13 to 0.57 ± 0.20 postoperatively (average gain of 0.075 ± 0.14; P=.007) and improved from 0.92 ± 0.12 preoperatively to 0.93±0.15 after surgery (mean gain of 0.013 ± 0.14; P=.603) in the fellow nonamblyopic eyes. The safety index was significantly greater in the amblyopic eyes compared with the nonamblyopic fellow eyes (1.15 ± 0.30 vs 1.02 ± 0.15, P=.035), therefore, no difference was noted in efficacy (P=.913). Five of 30 eyes with mild to moderate amblyopia gained 2 to 4 lines of CDVA.
CONCLUSIONS:
laser refractive surgery for myopic correction was found to be safe and effective in eyes with mild to moderate amblyopia.
AuthorsFaik Oruçoğlu-Orucov, Joseph Frucht-Pery, David Landau, Eyal Strasman, Abraham Solomon
JournalJournal of refractive surgery (Thorofare, N.J. : 1995) (J Refract Surg) Vol. 27 Issue 1 Pg. 18-22 (Jan 2011) ISSN: 1081-597X [Print] United States
PMID20415286 (Publication Type: Comparative Study, Journal Article)
Topics
  • Adolescent
  • Adult
  • Amblyopia (physiopathology, surgery)
  • Anisometropia (physiopathology, surgery)
  • Female
  • Functional Laterality
  • Humans
  • Keratomileusis, Laser In Situ (methods)
  • Lasers, Excimer (therapeutic use)
  • Male
  • Middle Aged
  • Myopia (physiopathology, surgery)
  • Refraction, Ocular (physiology)
  • Retrospective Studies
  • Visual Acuity (physiology)
  • Young Adult

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