Abstract | INTRODUCTION: METHODS: Patients with other known liver diseases were excluded. Among 482 patients 429 were in the study group and 53 in the control group. RESULTS: In the study group the prevalence ofALT, GGT elevation and signs ofsteatosis was 12.1, 29.9, 38.3%, comparing to 5.7, 11.9 and 5.7% in the control group respectively. The differences were statistically significant. With the increasing number of risk factors we found growing prevalence of GGT elevation and signs of steatosis, but ALT elevation was equally prevalent. In multiple logistic regression the only independent predictor of ALT elevation was obesity, predictors of GGT elevation were type 2. diabetes and signs of steatosis, signs of steatosis were independently associated with overweight, obesity, type 2 diabetes and hypertriglyceridemia. CONCLUSIONS: Markers of liver disease do have a clinical and prognostic impact on the liver and cardiometabolic risk and therefore we suggest they should be actively screened in this group of patients.
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Authors | T Koller, J Kollerová, T Hlavatý, M Huorka, J Payer |
Journal | Vnitrni lekarstvi
(Vnitr Lek)
Vol. 56
Issue 3
Pg. 183-9
(Mar 2010)
ISSN: 0042-773X [Print] Czech Republic |
Vernacular Title | Prevalencia markerov polkodenia pecene u pacientov s metabolickými rizikovými faktormi. |
PMID | 20394204
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Biomarkers
(analysis)
- Fatty Liver
(complications, diagnosis)
- Female
- Humans
- Male
- Metabolic Syndrome
(complications)
- Middle Aged
- Risk Factors
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