Superselective arterial embolisation with a liquid polyvinyl alcohol copolymer in patients with acute gastrointestinal haemorrhage.

Abstract

OBJECTIVES:

To evaluate the results of emergency embolisation in acute arterial bleeding of the gastrointestinal tract with a liquid polyvinyl alcohol copolymer from two centres.

METHODS:

We retrospectively analysed 16 cases (15 patients) of acute arterial bleeding of the gastrointestinal tract where emergency embolotherapy was performed by using the copolymer when acute haemorrhage was not treatable with endoscopic techniques alone. Cause of haemorrhage and technical and clinical success were documented.

RESULTS:

Arterial embolotherapy was successful in all 16 cases. The technical success rate was 100%. The cause of bleeding was pancreatitis in four, graft-versus-host disease (GVHD) of the colon in three, malignancy in three, angiodysplasia in two, ulcer in two and panarteritis nodosa and trauma in one each. There were no procedure-related complications. No bowel necrosis occurred because of embolisation. In 13 cases, the patients were discharged in good condition (81%); the three patients with GVHD died because of the underlying disease.

CONCLUSIONS:

The copolymer seems to have great potential in embolotherapy of acute arterial gastrointestinal bleeding. In our series none of the patients had rebleeding at the site of embolisation and no clinically obvious bowel necrosis occurred.

• Authors: Markus Lenhart, Christian Paetzel, Michael Sackmann, Hans Schneider, Ernst Michael Jung, Andreas G Schreyer, Stefan Feuerbach, Niels Zorger
• Journal: European radiology (Eur Radiol) Vol. 20 Issue 8 Pg. 1994-9 (Aug 2010) ISSN: 1432-1084 [Electronic] Germany
• PMID: 20379821 (Publication Type: Evaluation Study, Journal Article, Multicenter Study)

Chemical References

• Hemostatics
• Onyx copolymer
• Polyvinyls
• Dimethyl Sulfoxide

Topics

• Acute Disease
• Dimethyl Sulfoxide (therapeutic use)
• Embolization, Therapeutic (methods)
• Female
• Gastrointestinal Hemorrhage (diagnostic imaging, therapy)
• Germany
• Hemostatics (administration & dosage)
• Humans
• Male
• Mesenteric Arteries
• Polyvinyls (therapeutic use)
• Radiography
• Retrospective Studies
• Treatment Outcome