Synthesis and characterization of collagen/hydroxyapatite: magnetite composite material for bone cancer treatment.

Abstract

Our purpose was obtaining and characterizing a complex composite system with multifunctional role: bone graft material and hyperthermia generator necessary for bone cancer therapy. The designed system was a magnetite enriched collagen/hydroxyapatite composite material, obtained by a co-precipitation method. Due to the applied electromagnetic field the magnetite will induce hyperthermia and cause tumoral cell apoptosis. The complex bone graft system was characterised by XRD, FTIR and SEM, while the hyperthermia was quantify by measuring the temperature increase due to the applied alternative electromagnetical field.

• Authors: Ecaterina Andronescu, Maria Ficai, Georgeta Voicu, Denisa Ficai, Maria Maganu, Anton Ficai
• Journal: Journal of materials science. Materials in medicine (J Mater Sci Mater Med) Vol. 21 Issue 7 Pg. 2237-42 (Jul 2010) ISSN: 1573-4838 [Electronic] United States
• PMID: 20372983 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Collagen
• Durapatite
• Ferrosoferric Oxide

Topics

• Bone Neoplasms (therapy)
• Bone Transplantation
• Bone and Bones
• Calcium Metabolism Disorders (therapy)
• Collagen (chemical synthesis, chemistry)
• Durapatite (chemical synthesis, chemistry)
• Extracellular Matrix
• Ferrosoferric Oxide