Complete remission of coronary vasculitis in Churg-Strauss Syndrome by prednisone and cyclophosphamide.

Abstract

The heart is involved in up to 50% of all patients with Churg-Strauss syndrome, but vasculitis of the coronary arteries has only been rarely documented. We present a young patient with severe coronary aneurysms and stenotic lesions due to a Churg-Strauss vasculitis. Prompt therapy with prednisone and cyclophosphamide resulted in the complete resolution of all lesions.

• Authors: Niels P Riksen, Helmut Gehlmann, Annemarie E Brouwer, Marcel van Deuren
• Journal: Clinical rheumatology (Clin Rheumatol) Vol. 32 Suppl 1 Pg. S41-2 (Mar 2013) ISSN: 1434-9949 [Electronic] Germany
• PMID: 20349259 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Immunosuppressive Agents
• Cyclophosphamide
• Prednisolone

Topics

• Adolescent
• Churg-Strauss Syndrome (complications, drug therapy, pathology)
• Coronary Disease (drug therapy, etiology, pathology)
• Coronary Vessels (drug effects, pathology)
• Cyclophosphamide (therapeutic use)
• Drug Therapy, Combination
• Glucocorticoids (therapeutic use)
• Humans
• Immunosuppressive Agents (therapeutic use)
• Male
• Prednisolone (therapeutic use)
• Remission Induction
• Treatment Outcome
• Vasculitis (drug therapy, etiology, pathology)