[The quality of life of patients with overactive bladder after local injections of botulinum toxin A--a preliminary report].

Abstract

OBJECTIVES:

The purpose of this work was to evaluate the quality of life of patients suffering from urge urinary incontinence resistant to anticholinergic therapy treated with intradetrusical injections of 200 U botulinum toxin A.

MATERIALS AND METHODS:

The study group consisted of 10 female patients who were diagnosed with urge urinary incontinence. Standard King's questionnaire was used for the assessment of the change in the quality of life after treatment. Questionnaires were filled in by all patients before the treatment and during control visits, 3 months after the injection of botulinum toxin A.

RESULTS:

Statistically significant improvement in the quality of life for the majority of the domains of King's questionnaire (except the evaluation of urinary incontinence impact on the general health condition and social relations) was observed in 7 out of 10 patients subjected to botulinum toxin therapy (p < 0.05).

CONCLUSIONS:

Based on the results of this study we can conclude that treatment of patients with urge urinary incontinence not responding to classical anticholinergic treatment with botulinum toxin causes a significant improvement in the quality of their life.

• Authors: Tomasz Rechberger, Paweł Miotła, Paweł Skorupski, Andrzej Wróbel, Jacek Tomaszewski
• Journal: Ginekologia polska (Ginekol Pol) Vol. 81 Issue 1 Pg. 24-30 (Jan 2010) ISSN: 0017-0011 [Print] Poland
• Vernacular Title: Jakość zycia pacjentek z pecherzem nadreaktywnym po zastosowaniu toksyny botulinowej--doniesienie wstepne.
• PMID: 20232695 (Publication Type: English Abstract, Journal Article)

Chemical References

• Neuromuscular Agents
• Botulinum Toxins, Type A

Topics

• Adult
• Botulinum Toxins, Type A (administration & dosage)
• Female
• Humans
• Injections, Intralesional
• Middle Aged
• Muscle Contraction (drug effects)
• Neuromuscular Agents (administration & dosage)
• Quality of Life
• Surveys and Questionnaires
• Treatment Outcome
• Urinary Bladder (drug effects)
• Urinary Incontinence (drug therapy)
• Urodynamics (drug effects)
• Women's Health