Abstract |
We examined effects of hypocapnia on burst activity in the piriform-amygdala complex and C(4) inspiratory activity in limbic-brainstem-spinal cord preparations from 0- to 1-day-old rats. Hypocapnia (2% CO(2)) increased the burst rate in the piriform-amygdala complex but decreased the C(4) inspiratory burst rate. Since hyperventilation induces hypocapnia, and enhanced amygdala activity may be involved in induction of a sense of anxiety, our findings might explain the neuronal mechanism of a vicious circle between hyperventilation and an increased sense of anxiety.
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Authors | T Fujii, H Onimaru, M Suganuma, I Homma |
Journal | Advances in experimental medicine and biology
(Adv Exp Med Biol)
Vol. 669
Pg. 333-6
( 2010)
ISSN: 0065-2598 [Print] United States |
PMID | 20217377
(Publication Type: Journal Article)
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Topics |
- Amygdala
(physiopathology)
- Animals
- Animals, Newborn
- Anxiety
(physiopathology, psychology)
- Brain Stem
(physiopathology)
- Hyperventilation
(physiopathology, psychology)
- Hypocapnia
(physiopathology, psychology)
- Inhalation
- Rats
- Rats, Wistar
- Spinal Cord
(physiopathology)
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