Abstract | PURPOSE: METHODS: A 74-year-old woman who, 12 years before, had been diagnosed with a yellow-gray lesion in the left eye (OS) presented in our department for OS decreased vision of recent onset. RESULTS: Upon a complete ophthalmologic examination including ultrasonography, fluorescein angiography (FA), and spectral domain optical coherence tomography (SD-OCT), the patient was diagnosed with retinal astrocytic hamartoma and coincident CNV on its foveal border. Six months after 3 monthly intravitreal ranibizumab injections, FA and OCT revealed the CNV closure and absence of intraretinal and subretinal fluid on the foveal border of the retinal astrocytic hamartoma. CONCLUSIONS: Associations between retinal astrocytic hamartoma and CNV have not been previously reported. Intravitreal ranibizumab injection appears an attractive therapeutic option for patients showing such an unusual association.
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Authors | Giuseppe Querques, Houda Kerrate, Nicolas Leveziel, Gabriel Coscas, Gisele Soubrane, Eric H Souied |
Journal | European journal of ophthalmology
(Eur J Ophthalmol)
2010 Jul-Aug
Vol. 20
Issue 4
Pg. 789-91
ISSN: 1120-6721 [Print] United States |
PMID | 20213614
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Angiogenesis Inhibitors
- Antibodies, Monoclonal
- Antibodies, Monoclonal, Humanized
- Ranibizumab
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Topics |
- Aged
- Angiogenesis Inhibitors
(administration & dosage)
- Antibodies, Monoclonal
(administration & dosage)
- Antibodies, Monoclonal, Humanized
- Choroidal Neovascularization
(diagnosis, drug therapy, etiology)
- Female
- Fluorescein Angiography
- Follow-Up Studies
- Hamartoma
(complications, diagnosis)
- Humans
- Intravitreal Injections
- Ranibizumab
- Retinal Diseases
(complications, diagnosis)
- Tomography, Optical Coherence
- Visual Acuity
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