Cobalt catalysis at the crossroads: cobalt-catalyzed Alder-ene reaction versus [2 + 2] cycloaddition.

Abstract

The application of bidentate phosphine ligands in cobalt-catalyzed transformations of cyclic alkenes such as cyclopentene and cycloheptene with internal alkynes led to a chemoselective Alder-ene or a [2 + 2] cycloaddition reaction depending on the electronic nature of the alkyne and the bite angle of the ligand used.

• Authors: Gerhard Hilt, Anna Paul, Jonas Treutwein
• Journal: Organic letters (Org Lett) Vol. 12 Issue 7 Pg. 1536-9 (Apr 02 2010) ISSN: 1523-7052 [Electronic] United States
• PMID: 20196545 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Alkenes
• Organometallic Compounds
• Cobalt

Topics

• Alkenes (chemical synthesis, chemistry)
• Catalysis
• Cobalt (chemistry)
• Cyclization
• Molecular Structure
• Organometallic Compounds (chemistry)
• Stereoisomerism