[Acute generalized exanthematous pustulosis].

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous drug reaction often caused by beta-lactam antibiotics. The reaction is characterized by sudden occurrence of a generalized exanthema, developing within 1-2 days. Hundreds of sterile pustules arise on an oedematous and erythematous base. The cutaneous symptoms are accompanied by fever and neutrophilia. The pustules resolve within 4-10 days once the causative drug has been withdrawn. We hereby present a classical case of amoxicillin-induced AGEP in a 34-year-old woman.

• Authors: Lisbeth Rosholm Comstedt, Janni Hjortlund Gregersen, Anette Bygum
• Journal: Ugeskrift for laeger (Ugeskr Laeger) Vol. 172 Issue 8 Pg. 628-9 (Feb 22 2010) ISSN: 1603-6824 [Electronic] Denmark
• Vernacular Title: Akut generaliseret eksantematøs pustulose.
• PMID: 20184822 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Amoxicillin

Topics

• Acute Generalized Exanthematous Pustulosis (chemically induced, diagnosis, pathology)
• Adult
• Amoxicillin (adverse effects)
• Anti-Bacterial Agents (adverse effects)
• Diagnosis, Differential
• Female
• Humans