Symptomatic neonatal tetralogy of Fallot: repair or shunt?

Abstract

BACKGROUND:

The management of neonates with symptomatic tetralogy of Fallot (TOF) requiring surgical intervention in the first month of life remains controversial. We reviewed our experience with neonates 30 days or greater with TOF from 2002 to 2008 requiring surgical intervention.

METHODS:

Thirty-seven consecutive symptomatic nonrandomized neonates with TOF or its variants (including TOF with complete atrioventricular septal defect or absent pulmonary valve but excluding pulmonary atresia) had either a shunt (n = 17) or primary repair (n = 20). The shunted patients more commonly required emergency operation (24% vs 0%; p = 0.036); otherwise, the two groups were similar.

RESULTS:

One infant with preoperative bowel ischemia died one day postoperatively after emergency shunting. There were two late deaths 11 and 12 months postoperatively, both in primary repair patients. The 16 surviving shunted patients had TOF repair 216 +/- 99 days after the original shunt. The shunted patients had shorter intensive care unit and hospital stays for the first operation, which became equivalent when the second hospitalization (repair) values were added. The primary repair patients more frequently had a transannular patch and a tendency to more frequent delayed sternal closure. Four primary repair (20%) and two shunted (12.5%) patients required subsequent cardiac operations after complete repair (p = not significant).

CONCLUSIONS:

Shunting or primary repair of neonates with symptomatic TOF provides equivalent mortality and results. Shunted patients had fewer transannular patch repairs despite having more emergent initial operations. Compared with the primary repair group, shunted patients had decreased intensive care unit and hospital stays for the first hospitalization, which were neutralized when the second operation (repair) values were added.

• Authors: Kirk R Kanter, Brian E Kogon, Paul M Kirshbom, Pamela R Carlock
• Journal: The Annals of thoracic surgery (Ann Thorac Surg) Vol. 89 Issue 3 Pg. 858-63 (Mar 2010) ISSN: 1552-6259 [Electronic] Netherlands
• PMID: 20172143 (Publication Type: Journal Article)
• Copyright: 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Topics

• Cardiac Surgical Procedures (methods)
• Humans
• Infant, Newborn
• Intensive Care Units, Neonatal
• Length of Stay
• Palliative Care
• Reoperation
• Tetralogy of Fallot (complications, diagnosis, mortality, surgery)