Calcinosis cutis and Sjögren's syndrome.

Abstract

Cutaneous calcinosis can be classified into four types: dystrophic, metastatic, idiopathic and iatrogenic. Dystrophic calcification constitutes the most frequent variant and is associated with a large number of illnesses, among which are included some collagen diseases such as CREST syndrome, scleroderma, dermatomyositis and lupus erythematosus. We present a case of dystrophic calcinosis cutis, affecting the fingertip of a woman with a 10-year history of primary Sjögren's syndrome (SS). She has been receiving diltiazem as a treatment for the last 15 months, resulting in the partial resolution of the lesions. We emphasize the fact that the presence of calcinosis cutis has not been described previously in patients with SS, and that diltiazem has partially improved our patient's cutaneous lesions.

• Authors: M Llamas-Velasco, C Eguren, D Santiago, C García-García, J Fraga, A García-Diez
• Journal: Lupus (Lupus) Vol. 19 Issue 6 Pg. 762-4 (May 2010) ISSN: 1477-0962 [Electronic] England
• PMID: 20156928 (Publication Type: Case Reports, Journal Article)

Chemical References

• Calcium Channel Blockers
• Diltiazem

Topics

• Calcinosis (drug therapy, etiology, pathology)
• Calcium Channel Blockers (therapeutic use)
• Diltiazem (therapeutic use)
• Female
• Humans
• Middle Aged
• Sjogren's Syndrome (complications, pathology)
• Skin Diseases (drug therapy, etiology, pathology)