HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Retinal vasculitis associated with the anti-synthetase syndrome.

Abstract
A 50-year-old woman with a history of anti-Jo1-positive inflammatory myositis and interstitial lung disease presented with decreased vision in her right eye. Examination revealed white-centered hemorrhages scattered across the posterior pole in addition to several areas of vascular sheathing. Treatment was initiated with intravenous pulse solumedrol, with improvement in vision and resolution of the patient's white-centered hemorrhages. A thorough workup for other causes of vasculitis was unrevealing. Anti-synthetase syndrome is a serologically defined disorder clinically characterized by inflammatory myositis, interstitial lung disease, and other systemic findings. To our knowledge, retinal vasculitis has not been previously reported in patients with anti-synthetase syndrome.
AuthorsAhmad B Tarabishy, Mariam Khan, Matthew Bunyard, Careen Y Lowder
JournalOcular immunology and inflammation (Ocul Immunol Inflamm) Vol. 18 Issue 1 Pg. 16-8 (Jan 2010) ISSN: 1744-5078 [Electronic] England
PMID20128644 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antibodies, Antinuclear
  • Jo-1 antibody
  • Methylprednisolone Hemisuccinate
  • Histidine-tRNA Ligase
Topics
  • Antibodies, Antinuclear (blood)
  • Female
  • Histidine-tRNA Ligase (immunology)
  • Humans
  • Lung Diseases, Interstitial (diagnosis, drug therapy, pathology)
  • Methylprednisolone Hemisuccinate (therapeutic use)
  • Middle Aged
  • Myositis (diagnosis, drug therapy, pathology)
  • Retinal Vasculitis (diagnosis, drug therapy, pathology)
  • Syndrome
  • Visual Acuity

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: