Anticardiolipin antibodies: a study of frequency in TIA and stroke.

Abstract

We undertook a prospective study of consecutive patients to determine the frequency of elevated IgG and IgM anticardiolipin antibodies in transient ischemic attack and ischemic stroke and found elevated IgG antibodies in 8.2% (9 of 110) and IgM in 9.1% (10 of 110), only the former being significantly greater than in a healthy control population. We suggest that anticardiolipin screening be concentrated on the young.

• Authors: D C Hess, J Krauss, R J Adams, F T Nichols, D Zhang, H A Rountree
• Journal: Neurology (Neurology) Vol. 41 Issue 4 Pg. 525-8 (Apr 1991) ISSN: 0028-3878 [Print] United States
• PMID: 2011251 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antibodies
• Cardiolipins
• Immunoglobulin G

Topics

• Antibodies (analysis)
• Cardiolipins (immunology)
• Cerebrovascular Disorders (blood, immunology)
• Humans
• Immunoglobulin G (analysis)
• Ischemic Attack, Transient (blood, immunology)
• Middle Aged
• Partial Thromboplastin Time