[HTLV-I infection: ungual T-cell lymphoma as a primary manifestation].

Abstract

A 34-year-old woman presented with leathery thickening and haemorrhagic lesions of several finger- and toe-nails as first symptoms of an HTLV-I infection. Histology resembled that found in mycosis fungoides. Later signs of T cell deficiency (e.g. Pneumocystis carinii pneumonia) developed. An erythemato-papular exanthema representing T cell lymphoma with Pautrier's abscesses preceded her death 1 year later. The detection of HTLV-I antibodies helped to establish the diagnosis following initial confusion owing to elevation of the T-helper cells and the CD4/CD8 ratio.

• Authors: M Wolter, P Schleussner-Samuel, W C Marsch
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 42 Issue 1 Pg. 50-2 (Jan 1991) ISSN: 0017-8470 [Print] Germany
• Vernacular Title: HTLV-I-Infektion: unguales T-Zell-Lymphom als Primärmanifestation.
• PMID: 2010288 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Adult
• Female
• HTLV-I Infections (complications, diagnosis, pathology)
• Humans
• Lymphoma, T-Cell, Cutaneous (complications, pathology)
• Nail Diseases (complications)
• Skin Neoplasms (complications, pathology)