Abstract | IMPORTANCE OF THE FIELD: AREAS COVERED IN THIS REVIEW: The aim of this paper is to present a comprehensive and critical review of pharmacological and non-pharmacological treatments usually adopted in the management of OCD. MEDLINE and PubMed (1980 - 2009) databases were searched for English-language articles by using the following keywords: OCD, clomipramine, SSRIs, resistance, predictor of response, cognitive-behavioral therapy, exposure and response prevention, repetitive transcranial magnetic stimulation, deep brain stimulation, neurosurgery, electroconvulsive therapy. WHAT THE READER WILL GAIN: The reader will gain an exhaustive review of the advantages and disadvantages of the treatments usually adopted in OCD, with a special focus on resistance and clinical features that can be used as predictors of response. TAKE HOME MESSAGE:
Obsessive-compulsive disorder is a common psychiatric condition that can be adequately managed with the currently available therapeutic options. Although a certain percentage of patients do not achieve complete clinical remission, improvement of some of their core symptoms permits them to live more satisfying lives and to reach a better social adjustment.
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Authors | Donatella Marazziti, Giorgio Consoli |
Journal | Expert opinion on pharmacotherapy
(Expert Opin Pharmacother)
Vol. 11
Issue 3
Pg. 331-43
(Feb 2010)
ISSN: 1744-7666 [Electronic] England |
PMID | 20102301
(Publication Type: Journal Article, Review)
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Chemical References |
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Topics |
- Clinical Trials as Topic
- Clomipramine
(therapeutic use)
- Cognitive Behavioral Therapy
- Combined Modality Therapy
- Deep Brain Stimulation
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Electric Stimulation Therapy
- Electroconvulsive Therapy
- Electroshock
- Evidence-Based Medicine
- Humans
- Meta-Analysis as Topic
- Obsessive-Compulsive Disorder
(therapy)
- Randomized Controlled Trials as Topic
- Transcranial Magnetic Stimulation
- Treatment Outcome
- Vagus Nerve
(radiation effects)
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