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Closure of a bronchopleural fistula with bronchoscopic instillation of tetracycline.

Abstract
Persistent bronchopleural fistulas (BPF) due to infection, trauma, or thoracic surgical procedures are often difficult to manage. We report a patient with fulminant Staphylococcus aureus pneumonia complicated by chronic BPF formation which prevented weaning from mechanical ventilation due to severe air leak. Fistula closure was obtained by instillation of tetracycline into the fistula via a fiberoptic bronchoscope using a balloon catheter and blood clot occlusion technique. This closed the BPF and allowed successful weaning from mechanical ventilation.
AuthorsW R Martin, A D Siefkin, R Allen
JournalChest (Chest) Vol. 99 Issue 4 Pg. 1040-2 (Apr 1991) ISSN: 0012-3692 [Print] United States
PMID2009764 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Tetracycline
Topics
  • Adolescent
  • Bronchial Fistula (etiology, therapy)
  • Bronchoscopy
  • Fistula (etiology, therapy)
  • Humans
  • Instillation, Drug
  • Male
  • Pleural Diseases (etiology, therapy)
  • Pneumonia, Staphylococcal (complications)
  • Sclerotherapy
  • Tetracycline (administration & dosage, therapeutic use)

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