Abstract | BACKGROUND: METHODS: Twenty-four women undergoing breast cancer surgery performed a mobilization procedure before and 30 min after surgery, with measurement of arterial pressure, stroke volume (SV), cardiac output (CO), and total peripheral resistance (TPR) (Modelflow), besides evaluation of cerebral and muscle oxygenation (near-infrared spectroscopy) and recording of symptoms of orthostatic intolerance. RESULTS: There were no differences in the cardiovascular response and tissue oxygenation before and 30 min after surgery (P>0.05). Upon mobilization, systolic arterial pressure, SV, CO, and cerebral and muscle oxygenation decreased (P<0.05), whereas heart rate increased without change in TPR. After surgery, one patient (4%) experienced orthostatic intolerance, and one patient could not complete the mobilization procedure after surgery because of sedation. CONCLUSIONS:
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Authors | R G Müller, M Bundgaard-Nielsen, H Kehlet |
Journal | British journal of anaesthesia
(Br J Anaesth)
Vol. 104
Issue 3
Pg. 298-304
(Mar 2010)
ISSN: 1471-6771 [Electronic] England |
PMID | 20061313
(Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Aged
- Blood Pressure
(physiology)
- Breast Neoplasms
(surgery)
- Dizziness
(etiology)
- Early Ambulation
(adverse effects)
- Female
- Heart Rate
(physiology)
- Humans
- Mastectomy
(rehabilitation)
- Middle Aged
- Oxygen Consumption
(physiology)
- Perioperative Care
(methods)
- Postoperative Care
(adverse effects)
- Stroke Volume
(physiology)
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